| Model NO.: | Cartap14778 |
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| Customization: | Available Customized Request |
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cartap Common name: cartap IUPAC name: S,S'-(2-dimethylaminotrimethylene) bis(thiocarbamate) Chemical Abstracts name: S,S'-[2-(dimethylamino)-1,3-propanediyl] dicarbamothioate CAS RN: [15263-53-3] cartap hydrochloride Common name: cartap hydrochloride CAS RN: [15263-52-2] cartap monohydrochloride; [22042-59-7] cartap, unspecified hydrochloride PHYSICAL CHEMISTRY Cartap Mol. wt.: 237.3; M.f.: C7H15N3O2S2 Cartap hydrochloride Mol. wt.: 273.8; M.f.: C7H16ClN3O2S2; Form: Colourless crystalline, slightly hygroscopic solid with slight odour. M.p.: 179-181 ºC (decomp.) V.p.: Negligible; Solubility: In water c. 200 g/l (25 ºC). Very slightly soluble in methanol and ethanol. Insoluble in acetone, diethyl ether, ethyl acetate, chloroform, benzene, and hexane. Stability: Stable in acidic conditions, but hydrolysed in neutral or alkaline media. APPLICATIONS Biochemistry: Analogue or propesticide of the natural toxin nereistoxin. Nicotinergic acetylcholine blocker, causing paralysis by blocking cholinergic transmissions in the central nervous systems of insects. Mode of action: Systemic insecticide with stomach and contact action. Insects discontinue feeding, and die of starvation. cartap hydrochloride Uses: Cartap hydrochloride is used, at c. 0.4-1.0 kg/ha, for control of chewing and sucking insects (particularly Lepidoptera and Coleoptera), at almost all stages of development, on many crops, including rice (Chilo suppressalis, Cnaphalocrocis medinalis, Lissorhoptrus oryzophilus and rice-leaf beetle), potatoes, cabbage and other vegetables (Agromyzidae, Leptinotarsa decemlineata and Plutella xylostella); also on soya beans, peanuts, sunflowers, maize, sugar beet, wheat, pearl barley, pome fruit, stone fruit, citrus fruit, vines, chestnuts, ginger, tea, cotton, and sugar cane. Phytotoxicity: May be phytotoxic to cotton, tobacco, and apples, under certain soil and climatic conditions. Formulation types: DP; GR; SP. Compatibility: Not compatible with pesticides which are alkaline. MAMMALIAN TOXICOLOGY cartap hydrochloride Oral: Acute oral LD50 for male rats 345, female rats 325, male mice 150, female mice 154 mg/kg. Skin and eye: Acute percutaneous LD50 for mice >1000 mg/kg; no irritation to skin or eyes in rabbits. Inhalation: LC50 (6 h) for rats >0.54 mg/l. NOEL: (2 y) for rats 10 mg/kg b.w. daily; (1.5 y) for mice 20 mg/kg b.w. daily. Toxicity class: WHO (a.i.) II; EPA (formulation) II EC hazard Xn; R21/22 ECOTOXICOLOGY cartap hydrochloride Fish: LC50 for carp 1.6 mg/l (24 h) and 1.0 mg/l (48 h). Other aquatic spp.: LC50 (24 h) for Moina macrocopa 12.5-25 mg/l. Bees: Moderately toxic to honeybees. ENVIRONMENTAL FATE Animals: In rats, the carbonyl carbon is hydrolysed, and the sulfur oxidised, with N-demethylation of thiomethyl derivatives. No accumulation occurs in tissues. Rapidly excreted in the urine. Soil/Environment: DT50 in soil c. 3 d.
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